TCAS
Toxicology Consultants & Assessment Specialists, LLC

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Drugs of Abuse   Toxic Substances: Drugs of Abuse
Drugs of abuse are well-documented in the peer-reviewed toxicological literature. a TCAS has provided toxicological guidance, written assessments and expert testimony in hundreds of drug-related cases. Virtually all drugs of abuse are well-documented in the peer-reviewed toxicological literature with clearly-established endpoints. However, drugs of... (more)

Toxicology of Pharmaceuticals   Toxic Substances: Toxicology of Pharmaceuticals
TCAS has broad experience with pharmaceutical toxicology. a TCAS has wide experience with pharmaceutical toxicology and has performed many assessments involving prescription medications, drugs of abuse, vaccines and over-the-counter preparations. Although pharmaceutical use can be a significant toxicological factor in a variety of claims, the real... (more)

Polypharmacology Induces   Case Studies in Toxicology: Polypharmacology Induces "Sleep Driving"
This case study illustrates the role of toxicological weight-of-evidence WOE in a motor vehicle accident case involving multiple pharmaceuticals. It also illustrates how drug interactions can be considered evidential in a toxicological causation assessment. Multiple pharmaceutical interactions carry an imprecise risk of driving impairment. a On the... (more)

Professional Experience and Toxicological Specializations   Professional Experience and Toxicological Specializations
TCAS has assessed hundreds of different types of toxic substances and exposure effects. [a] TCAS provides professional, comprehensive forensic and environmental exposure analysis, risk assessments and causation determinations. With more than 30 years of hands-on experience, our cases cover a vast range of toxic exposure-related issues combining toxicological... (more)

Site Map   Site Map
Toxicology Consultants and Assessment Specialists, LLC TCAS has devoted its website to the role of the expert toxicologist and the science of toxicology. The following pages present both original and edited public-domain information compiled as a useful educational resource. This site map is a content reference intended to assist with rapid location... (more)

A Message from Dr. William R. Sawyer
Chief Toxicologist, TCAS, LLC

A message from Dr. William R. Sawyer, Expert Toxicologist

"Assessing the direct and indirect impacts of drugs of abuse requires close attention to detail. Adhering to generally-accepted, peer-reviewed methods and the results of human studies are the best ways to ensure credible results that will stand up to scientific scrutiny."

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This is an informational and instructional website devoted to toxicology. It presents both original and edited public-domain content compiled as a useful educational resource. References and footnotes have been included wherever possible and image sources have been cited where appropriate. Although most pages can be printed or downloaded as PDF files (and we encourage you to make constructive use of our information), this website is copyrighted and material may only be reproduced and/or distributed with prior permission from TCAS, LLC.